Phenotypes associated with this allele

• Allele Symbol: Tbx18^tm1Sev
• Allele Name: targeted mutation 1, Sylvia Evans
• Allele ID: MGI:3801039
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Tbx18^tm1Sev/Tbx18^tm1.1Sev	involves: 129S4/SvJaeSor	MGI:5529161

Genotype
MGI:5529161

ht1

• Allelic Composition: Tbx18^tm1Sev/Tbx18^tm1.1Sev
• Genetic Background: involves: 129S4/SvJaeSor

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

perinatal lethality ( J:196480 )

• pups die soon after birth as result of skeletal abnormalities and respiratory distress

growth/size/body

decreased body length ( J:196480 )

• body length is shortened compared to wild-type at birth

integument

integument phenotype ( J:196480 )

N • at E18.5, no differences in hair follicle morphology, total follicle numbers or follicle subtypes from all 3 waves relative to wild-type are observed

skeleton

abnormal skeleton morphology ( J:196480 )

respiratory system

respiratory distress ( J:196480 )

• observed at birth; contributes to postnatal death