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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mmom2C57BL/6J
C57BL/6J
MGI:3802646
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		ApcMin/Apc+
Mmom2129X1/SvJ/Mmom2C57BL/6J 		involves: 129X1/SvJ * C57BL/6J MGI:3803126
cx2
 		ApcMin/Apc+
Mmom2C57BL/6J/Mmom2FVB/NTac 		involves: C57BL/6J * FVB/NTac MGI:3803125
cx3
 		ApcMin/Apc+
Mmom2C57BL/6J/Mmom2FVB/NTac
Mmom3C57BL/6J/Mmom3FVB/NTac 		involves: C57BL/6J * FVB/NTac MGI:3803127
cx4
 		ApcMin/Apc+
Mmom2C57BL/6J/Mmom2FVB/NTac
Mmom4C57BL/6J/Mmom4FVB/NTac 		involves: C57BL/6J * FVB/NTac MGI:3803128


Genotype
MGI:3803126
cx1
Allelic
Composition		 ApcMin/Apc+
Mmom2129X1/SvJ/Mmom2C57BL/6J
Genetic
Background		 involves: 129X1/SvJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
ApcMin mutation (12 available); any Apc mutation (158 available)
Mmom2129X1/SvJ mutation (0 available); any Mmom2 mutation (0 available)
Mmom2C57BL/6J mutation (0 available); any Mmom2 mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
decreased mammary gland tumor incidence ( J:128481 )
• decreased mammary tumor number after ENU treatment compared to C57BL/6J-homozygous females
• increased tumor latency

integument
decreased mammary gland tumor incidence ( J:128481 )
• decreased mammary tumor number after ENU treatment compared to C57BL/6J-homozygous females
• increased tumor latency

endocrine/exocrine glands
decreased mammary gland tumor incidence ( J:128481 )
• decreased mammary tumor number after ENU treatment compared to C57BL/6J-homozygous females
• increased tumor latency




Genotype
MGI:3803125
cx2
Allelic
Composition		 ApcMin/Apc+
Mmom2C57BL/6J/Mmom2FVB/NTac
Genetic
Background		 involves: C57BL/6J * FVB/NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
ApcMin mutation (12 available); any Apc mutation (158 available)
Mmom2C57BL/6J mutation (0 available); any Mmom2 mutation (0 available)
Mmom2FVB/NTac mutation (0 available); any Mmom2 mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
decreased mammary gland tumor incidence ( J:128481 )
• 24% decrease in mammary tumor number after ENU treatment compared to C57BL/6J-homozygous females
• increased tumor latency

endocrine/exocrine glands
decreased mammary gland tumor incidence ( J:128481 )
• 24% decrease in mammary tumor number after ENU treatment compared to C57BL/6J-homozygous females
• increased tumor latency

integument
decreased mammary gland tumor incidence ( J:128481 )
• 24% decrease in mammary tumor number after ENU treatment compared to C57BL/6J-homozygous females
• increased tumor latency




Genotype
MGI:3803127
cx3
Allelic
Composition		 ApcMin/Apc+
Mmom2C57BL/6J/Mmom2FVB/NTac
Mmom3C57BL/6J/Mmom3FVB/NTac
Genetic
Background		 involves: C57BL/6J * FVB/NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
ApcMin mutation (12 available); any Apc mutation (158 available)
Mmom2C57BL/6J mutation (0 available); any Mmom2 mutation (0 available)
Mmom2FVB/NTac mutation (0 available); any Mmom2 mutation (0 available)
Mmom3C57BL/6J mutation (0 available); any Mmom3 mutation (0 available)
Mmom3FVB/NTac mutation (0 available); any Mmom3 mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
decreased mammary gland tumor incidence ( J:128481 )
• decreased mammary tumor number after ENU treatment compared to C57BL/6J-homozygous females

endocrine/exocrine glands
decreased mammary gland tumor incidence ( J:128481 )
• decreased mammary tumor number after ENU treatment compared to C57BL/6J-homozygous females

integument
decreased mammary gland tumor incidence ( J:128481 )
• decreased mammary tumor number after ENU treatment compared to C57BL/6J-homozygous females




Genotype
MGI:3803128
cx4
Allelic
Composition		 ApcMin/Apc+
Mmom2C57BL/6J/Mmom2FVB/NTac
Mmom4C57BL/6J/Mmom4FVB/NTac
Genetic
Background		 involves: C57BL/6J * FVB/NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
ApcMin mutation (12 available); any Apc mutation (158 available)
Mmom2C57BL/6J mutation (0 available); any Mmom2 mutation (0 available)
Mmom2FVB/NTac mutation (0 available); any Mmom2 mutation (0 available)
Mmom4C57BL/6J mutation (0 available); any Mmom4 mutation (0 available)
Mmom4FVB/NTac mutation (0 available); any Mmom4 mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
decreased mammary gland tumor incidence ( J:128481 )
• increased tumor latency after ENU treatment compared to C57BL/6J-homozygous females

endocrine/exocrine glands
decreased mammary gland tumor incidence ( J:128481 )
• increased tumor latency after ENU treatment compared to C57BL/6J-homozygous females

integument
decreased mammary gland tumor incidence ( J:128481 )
• increased tumor latency after ENU treatment compared to C57BL/6J-homozygous females




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory