About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hbbtm4(HBB*)Tow
targeted mutation 4, Timothy Townes
MGI:3802947
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Hbatm1(HBA)Tow/Hbatm1(HBA)Tow
Hbbtm4(HBB*)Tow/Hbbtm4(HBB*)Tow 		Not Specified MGI:3803749


Genotype
MGI:3803749
cx1
Allelic
Composition		 Hbatm1(HBA)Tow/Hbatm1(HBA)Tow
Hbbtm4(HBB*)Tow/Hbbtm4(HBB*)Tow
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hbatm1(HBA)Tow mutation (3 available); any Hba mutation (10 available)
Hbbtm4(HBB*)Tow mutation (0 available); any Hbb mutation (47 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
anemia ( J:137709 )
• slightly thalassemic
abnormal erythrocyte physiology ( J:137709 )
• modest but significant increase in erythrocyte oxygen affinity

cardiovascular system
cardiovascular system phenotype ( J:137709 )
N
• despite the absence of S-nitrosohemoglobin no signs of pulmonary hypertension or changes in hypoxic vasodilation response are seen




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory