immune system
• mice develop abnormal lung pathology starting at 5 months of age
• there is substantial peribronchial and perivascular infiltration of macrophages, B cells and CD4 T cells in the lungs
• in some mice, Charcot-Leyden like crystals are found in the airway
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respiratory system
• mice develop abnormal lung pathology starting at 5 months of age
• there is substantial peribronchial and perivascular infiltration of macrophages, B cells and CD4 T cells in the lungs
• in some mice, Charcot-Leyden like crystals are found in the airway
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• increased mucus production occurs in the lung in conjuction with lung inflammation
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