Analysis Tools
reproductive system
 |
• in male chimera mice
|
small testis
(
J:137707
)
|
|
• testes size and weight in male chimeras are reduced by more than 50% compared to wild-type mice
|
|
|
• testes size and weight in male chimeras are reduced by more than 50% compared to wild-type mice
|
azoospermia
(
J:137707
)
|
|
• in male chimera mice, testicular sperm are absent from the tubule lumen and round cells rather than spermatozoa are present in the epididymal lumen
• in male chimera mice, apoptosis of spermatocytes in the testes is increased 6- to 8.5-fold compared to in wild-type mice
|
|
|
• in male chimera mice, seminiferous tubules lack elongating and elongated spermatid
|
|
|
• in male chimera mice, spermatogenesis is arrested at step 7 leading to increased apoptosis
|
|
|
• haploinsufficient male chimera mice are infertile
|
endocrine/exocrine glands
|
|
• in male chimera mice
|
small testis
(
J:137707
)
|
|
• testes size and weight in male chimeras are reduced by more than 50% compared to wild-type mice
|
|
|
• testes size and weight in male chimeras are reduced by more than 50% compared to wild-type mice
|
cellular
azoospermia
(
J:137707
)
|
|
• in male chimera mice, testicular sperm are absent from the tubule lumen and round cells rather than spermatozoa are present in the epididymal lumen
• in male chimera mice, apoptosis of spermatocytes in the testes is increased 6- to 8.5-fold compared to in wild-type mice
|
|
|
• in male chimera mice, seminiferous tubules lack elongating and elongated spermatid
|
