Phenotypes associated with this allele

• Allele Symbol: Tg(CAG-GFP/MAPT)1Pa
• Allele Name: transgene insertion 1, Virginia Papaioannou
• Allele ID: MGI:3804664
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Tbx6^tm2Pa/Tbx6^tm2Pa Tg(CAG-GFP/MAPT)1Pa/?	involves: 129 * 129S1/Sv * 129X1/SvJ * ICR	MGI:3804668

Genotype
MGI:3804668

cx1

• Allelic Composition: Tbx6^tm2Pa/Tbx6^tm2Pa; Tg(CAG-GFP/MAPT)1Pa/?
• Genetic Background: involves: 129 * 129S1/Sv * 129X1/SvJ * ICR

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

decreased embryonic cilium length ( J:137163 )

• image trace analysis suggests an increase in the number of short cilia

abnormal motile primary cilium physiology ( J:137163 )

• embryonic cilia on the periphery of Henson's node show a decrease in the proportion of motile cilia with regular motion and an increase in the proportion of erratically moving cilia

• in the pit of the node the proportion of nonmotile and erratically moving cilia is increased and the proportion of motile cilia with regular motion is decreased

abnormal embryo development ( J:137163 )

• intracellular calcium asymmetries normally present around the node are absent

cellular

decreased embryonic cilium length ( J:137163 )

• image trace analysis suggests an increase in the number of short cilia

abnormal motile primary cilium physiology ( J:137163 )

• embryonic cilia on the periphery of Henson's node show a decrease in the proportion of motile cilia with regular motion and an increase in the proportion of erratically moving cilia

• in the pit of the node the proportion of nonmotile and erratically moving cilia is increased and the proportion of motile cilia with regular motion is decreased