Phenotypes associated with this allele

• Allele Symbol: Myod1^tm1Ahb
• Allele Name: targeted mutation 1, Annick Harel-Bellan
• Allele ID: MGI:3804837
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Myod1^tm1Ahb/Myod1^tm1Ahb	Not Specified	MGI:3804941

Genotype
MGI:3804941

hm1

• Allelic Composition: Myod1^tm1Ahb/Myod1^tm1Ahb
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

abnormal muscle morphology ( J:116060 )

• the number of satellite-cell-derived primary myoblasts from the limbs and diaphragm is 2-3 fold higher than in wild-type

abnormal muscle physiology ( J:116060 )

• although the number of satellite-cell-derived primary myoblasts from the limbs and diaphragm is 2-3 fold higher than in wild-type, their differentiation is reduced as indicated by marker analysis

• differentiating myoblasts derived from the diaphragm show a defect in fusion

delayed skeletal muscle regeneration ( J:116060 )

• adults show delayed skeletal muscle regeneration in vivo after cardiotoxin injection