Analysis Tools|
Allele Symbol Allele Name Allele ID |
Bhlhe41tm1Mjro targeted mutation 1, Moritz J Rossner MGI:3805461 |
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| Summary |
4 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• following an 8 hours light dark cycle delay (experimental jet lag), mice exhibit a delayed behavioral re-entrainment compared to wild-type mice that is not as severe as in Bhlhb2tm1Tan homozygotes or compound Bhlhb2 and Blbhb3 mice
• however, rhythmicity of wheel running during light dark and dark dark phases is normal
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|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• free-running period length in constant darkness following light dark entrainment is lengthened compared to in wild-type mice
• however, rhythmicity of wheel running during light dark and dark dark phases is normal
|
|
• phase shift responses are lengthened
• however, the photic phase response curve is normal
• following an 8 hours light dark cycle delay (experimental jet lag), mice exhibit significant delayed behavioral re-entrainment compared to wild-type mice
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• free-running period length in constant darkness following light dark entrainment is lengthened compared to in wild-type mice
• however, rhythmicity of wheel running during light dark and dark dark phases is normal
|
|
• following an 8 hours light dark cycle delay (experimental jet lag), mice exhibit significant delayed behavioral re-entrainment compared to wild-type mice that is not greater than in Bhlhb2tm1Tan homozygotes
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• free-running period length in constant darkness following light dark entrainment is lengthened compared to in wild-type mice
• however, rhythmicity of wheel running during light dark and dark dark phases is normal
|
|
• following an 8 hours light dark cycle delay (experimental jet lag), mice exhibit significant delayed behavioral re-entrainment compared to wild-type mice that is not greater than in Bhlhb2tm1Tan homozygotes
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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