Phenotypes associated with this allele

• Allele Symbol: Igh^{tm1(Ighppc1-5)Cche}
• Allele Name: targeted mutation 1, Ching Chen
• Allele ID: MGI:3805804
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Igh^tm1(Ighppc1-5)Cche/Igh^+	B6.Cg-Igh^tm1(Ighppc1-5)Cche	MGI:3805805

Genotype
MGI:3805805

ht1

• Allelic Composition: Igh^{tm1(Ighppc1-5)Cche}/Igh⁺
• Genetic Background: B6.Cg-Igh^{tm1(Ighppc1-5)Cche}

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

immune system phenotype ( J:138356 )

N • despite the rearrangement, mice exhibit normal non-autoantibody B cell development and function

increased autoantibody level ( J:138356 )

• mice exhibit an increase in the number of autoantibody B cells in the spleen, lymph node and peripheral blood compared to in wild-type mice