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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(MC1R)1Jkn
transgene insertion 1, Ian J Jackson
MGI:3805878
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		a/A
Mc1re/Mc1re
Pomctm1Sora/Pomctm1Sora
Tg(MC1R)1Jkn/? 		involves: 129S6/SvEvTac * C57BL/6Ha MGI:3805942
cx2
 		a/a
Mc1re/Mc1re
Pomctm1Sora/Pomctm1Sora
Tg(MC1R)1Jkn/? 		involves: 129S6/SvEvTac * C57BL/6Ha MGI:3805943
cx3
 		Ay-Jkn/A
Mc1re/Mc1re
Tg(MC1R)1Jkn/0 		involves: C57BL/6Ha * C57BL/6N MGI:3805939


Genotype
MGI:3805942
cx1
Allelic
Composition		 a/A
Mc1re/Mc1re
Pomctm1Sora/Pomctm1Sora
Tg(MC1R)1Jkn/?
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6Ha
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (229 available); any a mutation (463 available)
A mutation (19 available); any a mutation (463 available)
Mc1re mutation (4 available); any Mc1r mutation (44 available)
Pomctm1Sora mutation (0 available); any Pomc mutation (21 available)
Tg(MC1R)1Jkn mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
yellow coat color ( J:129904 )
• mice have a much more yellow coat than agouti controls
abnormal hair follicle pheomelanosome pheomelanin content ( J:129904 )
• the phaeomelanin to total melanin ratio is higher (2.00) than in agouti controls (0.19)

integument
yellow coat color ( J:129904 )
• mice have a much more yellow coat than agouti controls
abnormal hair follicle pheomelanosome pheomelanin content ( J:129904 )
• the phaeomelanin to total melanin ratio is higher (2.00) than in agouti controls (0.19)




Genotype
MGI:3805943
cx2
Allelic
Composition		 a/a
Mc1re/Mc1re
Pomctm1Sora/Pomctm1Sora
Tg(MC1R)1Jkn/?
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6Ha
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (229 available); any a mutation (463 available)
Mc1re mutation (4 available); any Mc1r mutation (44 available)
Pomctm1Sora mutation (0 available); any Pomc mutation (21 available)
Tg(MC1R)1Jkn mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
yellow coat color ( J:129904 )
• mice have a much more yellow coat than agouti controls
abnormal hair follicle pheomelanosome pheomelanin content ( J:129904 )
• the phaeomelanin to total melanin ratio is higher (1.74) than in controls (0.20)

integument
yellow coat color ( J:129904 )
• mice have a much more yellow coat than agouti controls
abnormal hair follicle pheomelanosome pheomelanin content ( J:129904 )
• the phaeomelanin to total melanin ratio is higher (1.74) than in controls (0.20)




Genotype
MGI:3805939
cx3
Allelic
Composition		 Ay-Jkn/A
Mc1re/Mc1re
Tg(MC1R)1Jkn/0
Genetic
Background		 involves: C57BL/6Ha * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A mutation (19 available); any a mutation (463 available)
Ay-Jkn mutation (0 available); any a mutation (463 available)
Mc1re mutation (4 available); any Mc1r mutation (44 available)
Tg(MC1R)1Jkn mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
yellow coat color ( J:129904 )
• mice have a pale yellow coat color
• the yellow color is darker than what is observed in Ay-Jkn heterozygotes

integument
yellow coat color ( J:129904 )
• mice have a pale yellow coat color
• the yellow color is darker than what is observed in Ay-Jkn heterozygotes




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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory