About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Prdm14tm1Sait
targeted mutation 1, Mitinori Saitou
MGI:3805889
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Prdm14tm1Sait/Prdm14tm1Sait B6.129P2-Prdm14tm1Sait MGI:3805979
cn2
 		Prdm14tm1Sait/Prdm14tm1Sait
Tg(Prdm1-Venus)1Sait/0 		involves: 129P2/OlaHsd * C57BL/6 MGI:3805983


Genotype
MGI:3805979
hm1
Allelic
Composition		 Prdm14tm1Sait/Prdm14tm1Sait
Genetic
Background		 B6.129P2-Prdm14tm1Sait
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prdm14tm1Sait mutation (0 available); any Prdm14 mutation (51 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
absent germ cells ( J:138571 )
• at 11 weeks of age

cellular
absent germ cells ( J:138571 )
• at 11 weeks of age




Genotype
MGI:3805983
cn2
Allelic
Composition		 Prdm14tm1Sait/Prdm14tm1Sait
Tg(Prdm1-Venus)1Sait/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prdm14tm1Sait mutation (0 available); any Prdm14 mutation (51 available)
Tg(Prdm1-Venus)1Sait mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal primordial germ cell morphology ( J:138571 )
• primordial germ cells appear frail and their migration is delayed compared to in wild-type mice
• primordial germ cells exhibit reduced pluripotency and genetic re-programming compared to in wild-type mice

cellular
abnormal primordial germ cell morphology ( J:138571 )
• primordial germ cells appear frail and their migration is delayed compared to in wild-type mice
• primordial germ cells exhibit reduced pluripotency and genetic re-programming compared to in wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
08/21/2024
MGI 6.24 		The Jackson Laboratory