Phenotypes associated with this allele

• Allele Symbol: Prdm14^tm1Sait
• Allele Name: targeted mutation 1, Mitinori Saitou
• Allele ID: MGI:3805889
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Prdm14^tm1Sait/Prdm14^tm1Sait	B6.129P2-Prdm14^tm1Sait	MGI:3805979
cn2	Prdm14^tm1Sait/Prdm14^tm1Sait Tg(Prdm1-Venus)1Sait/0	involves: 129P2/OlaHsd * C57BL/6	MGI:3805983

Genotype
MGI:3805979

hm1

• Allelic Composition: Prdm14^tm1Sait/Prdm14^tm1Sait
• Genetic Background: B6.129P2-Prdm14^tm1Sait

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

absent germ cells ( J:138571 )

• at 11 weeks of age

female infertility ( J:138571 )

♀

male infertility ( J:138571 )

♂

cellular

absent germ cells ( J:138571 )

• at 11 weeks of age

Genotype
MGI:3805983

cn2

• Allelic Composition: Prdm14^tm1Sait/Prdm14^tm1Sait; Tg(Prdm1-Venus)1Sait/0
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

reproductive system

abnormal primordial germ cell morphology ( J:138571 )

• primordial germ cells appear frail and their migration is delayed compared to in wild-type mice

• primordial germ cells exhibit reduced pluripotency and genetic re-programming compared to in wild-type mice

decreased primordial germ cell number ( J:138571 )

cellular

abnormal primordial germ cell morphology ( J:138571 )

• primordial germ cells appear frail and their migration is delayed compared to in wild-type mice

• primordial germ cells exhibit reduced pluripotency and genetic re-programming compared to in wild-type mice

decreased primordial germ cell number ( J:138571 )