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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Hrm1Btlr
mutation 1, Bruce Beutler
MGI:3805975
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Hrm1Btlr/Hrm1Btlr C57BL/6J-Hrm1Btlr MGI:3805976


Genotype
MGI:3805976
hm1
Allelic
Composition
Hrm1Btlr/Hrm1Btlr
Genetic
Background
C57BL/6J-Hrm1Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hrm1Btlr mutation (1 available); any Hr mutation (87 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
N
• homozygous mutant mice have normal numbers of T-cells in the periphery

hematopoietic system
N
• homozygous mutant mice have normal numbers of T-cells in the periphery

integument
• mice homozygous for this mutation develop a normal first coat, but from two weeks of age begin to lose their hair starting just above the eyes and progressing posteriorly; by three weeks of age animals have an almost universal absence of hair, with occasional hairs retained on the feet and snout

limbs/digits/tail





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory