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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Icam4tm1Jach
targeted mutation 1, Joel Anne Chasis
MGI:3806488
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Icam4tm1Jach/Icam4tm1Jach involves: 129 * C57BL/6 MGI:3806553


Genotype
MGI:3806553
hm1
Allelic
Composition		 Icam4tm1Jach/Icam4tm1Jach
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Icam4tm1Jach mutation (0 available); any Icam4 mutation (8 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:138068 )
N
• despite decreased erythroblastic island formation, mice exhibit normal hematocrit, hemoglobin and red cell indices
abnormal erythropoiesis ( J:138068 )
• mice exhibit 47% decrease in erythroblastic island formation from bone marrow cells in culture and 64% in vivo compared to wild-type cells




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory