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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Crisp1tm1Pasc
targeted mutation 1, Patricia Cuasnicu
MGI:3808726
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Crisp1tm1Pasc/Crisp1tm1Pasc involves: 129S6/SvEvTac * C57BL/6N MGI:3808727


Genotype
MGI:3808727
hm1
Allelic
Composition		 Crisp1tm1Pasc/Crisp1tm1Pasc
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crisp1tm1Pasc mutation (0 available); any Crisp1 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:139154 )
N
• mice exhibit normal fertility, spermatogenesis, capacitation, and acrosomal reaction
abnormal sperm physiology ( J:139154 )
• the percent of zona pellucida intact or free eggs fertilized by sperm in vitro is lower than for wild-type sperm
• sperm exhibit reduced ability to fuse to eggs compared to wild-type sperm




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory