All Phenotypes Scn8a<M1Btlr> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Scn8a^M1Btlr
mutation 1, Bruce Beutler
MGI:3809770

Summary

2 genotypes

Allelic Composition	Scn8a^M1Btlr/Scn8a^M1Btlr
Genetic Background	C57BL/6J-Scn8a^M1Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn8a^M1Btlr mutation (0 available); any Scn8a mutation (99 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

tremors ( J:139714 )

• mice homozygous for this mutation exhibit tremors of variable intensity

abnormal gait ( J:139714 )

• homozygous mutant mice exhibit gait disturbances of variable severity

Allelic Composition	Scn8a^M1Btlr/Scn8a⁺
Genetic Background	C57BL/6J-Scn8a^M1Btlr

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn8a^M1Btlr mutation (0 available); any Scn8a mutation (99 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

tremors ( J:139714 )

• mice heterozygous for this mutation sometimes exhibit a mild tremor, which does not persist

abnormal gait ( J:139714 )

• heterozygous mutant mice sometimes exhibit a mild gait disturbance, which does not persist

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24