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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ube2kGt(XK109)Byg
gene trap XK109, BayGenomics
MGI:3809822
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ube2kGt(XK109)Byg/Ube2kGt(XK109)Byg involves: 129P2/OlaHsd MGI:3809831
ht2
 		Ube2kGt(XK109)Byg/Ube2k+ involves: 129P2/OlaHsd MGI:3809832


Genotype
MGI:3809831
hm1
Allelic
Composition		 Ube2kGt(XK109)Byg/Ube2kGt(XK109)Byg
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ube2kGt(XK109)Byg mutation (0 available); any Ube2k mutation (69 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased neuron apoptosis ( J:138978 )
• cortical neurons are completely resistant to amyloid-beta neurotoxicity unlike wild-type neurons

cellular
decreased neuron apoptosis ( J:138978 )
• cortical neurons are completely resistant to amyloid-beta neurotoxicity unlike wild-type neurons




Genotype
MGI:3809832
ht2
Allelic
Composition		 Ube2kGt(XK109)Byg/Ube2k+
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ube2kGt(XK109)Byg mutation (0 available); any Ube2k mutation (69 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased neuron apoptosis ( J:138978 )
• cortical neurons are partially resistant to amyloid-beta neurotoxicity unlike wild-type neurons

cellular
decreased neuron apoptosis ( J:138978 )
• cortical neurons are partially resistant to amyloid-beta neurotoxicity unlike wild-type neurons




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory