mortality/aging
N |
• homozygotes show no decrease in survival or other obvious phenotypes
|
Allele Symbol Allele Name Allele ID |
Stx1atm2.1Sud targeted mutation 2.1, Thomas C Sudhof MGI:3809921 |
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Summary |
2 genotypes
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|
♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
N |
• homozygotes show no decrease in survival or other obvious phenotypes
|
|
|
♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• a 20% increase in size of the postsynaptic density is observed compared to cultured cortical neurons with wild type Stx1a
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• about a 25% increase in synaptic vesicle docking at synapses in cultured cortical neurons compared to controls
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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