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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Tek-cre)2352Rwng
transgene insertion 2352, Rong Wang
MGI:3810530
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Gt(ROSA)26Sortm1(CAG-Rhoj,-EGFP)Auem/Gt(ROSA)26Sor+
Tg(Tek-cre)2352Rwng/0 		involves: C57BL/6NCrlj * CBA/JNCrlj * FVB/N MGI:5464992
tg2
 		Tg(Tek-cre)2352Rwng/0 involves: FVB/N MGI:3810741


Genotype
MGI:5464992
cn1
Allelic
Composition		 Gt(ROSA)26Sortm1(CAG-Rhoj,-EGFP)Auem/Gt(ROSA)26Sor+
Tg(Tek-cre)2352Rwng/0
Genetic
Background		 involves: C57BL/6NCrlj * CBA/JNCrlj * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(CAG-Rhoj,-EGFP)Auem mutation (0 available); any Gt(ROSA)26Sor mutation (993 available)
Tg(Tek-cre)2352Rwng mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Retardation of retinal vascular growth in Gt(ROSA)26Sortm1(CAG-Rhoj,-EGFP)Auem/Gt(ROSA)26Sor+ Tg(Tek-cre)2352Rwng/0 mice

cardiovascular system
abnormal retina vasculature morphology ( J:191977 )
• retinal vascular growth retardation (reduced radial extension) at P4

vision/eye
abnormal retina vasculature morphology ( J:191977 )
• retinal vascular growth retardation (reduced radial extension) at P4




Genotype
MGI:3810741
tg2
Allelic
Composition		 Tg(Tek-cre)2352Rwng/0
Genetic
Background		 involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Tek-cre)2352Rwng mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:104401 )
• hemizygous mice are viable and fertile and show no overt abnormalities




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory