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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Bmp4tm2.1Blh
targeted mutation 1, Brigid L Hogan
MGI:3811252
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		Bmp4tm5.1Bhr/Bmp4tm2.1Blh involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster MGI:4460797
cx2
 		Bmp4tm2.1Blh/Bmp4+
Slc27a4pskn/Slc27a4pskn 		involves: 129S6/SvEvTac * FVB/N MGI:5475249


Genotype
MGI:4460797
ht1
Allelic
Composition		 Bmp4tm5.1Bhr/Bmp4tm2.1Blh
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * CBA * Swiss Webster
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmp4tm2.1Blh mutation (0 available); any Bmp4 mutation (23 available)
Bmp4tm5.1Bhr mutation (0 available); any Bmp4 mutation (23 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, complete penetrance ( J:159629 )
• no live born double mutant heterozygous animal when intecrossed two heterozygous parents

embryo
embryonic growth retardation ( J:159629 )
• at E9.5 resembling the homozygous null phenotype

growth/size/body
embryonic growth retardation ( J:159629 )
• at E9.5 resembling the homozygous null phenotype




Genotype
MGI:5475249
cx2
Allelic
Composition		 Bmp4tm2.1Blh/Bmp4+
Slc27a4pskn/Slc27a4pskn
Genetic
Background		 involves: 129S6/SvEvTac * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmp4tm2.1Blh mutation (0 available); any Bmp4 mutation (23 available)
Slc27a4pskn mutation (0 available); any Slc27a4 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
decreased hair follicle number ( J:194779 )
• of secondary hair follicles at E16.5

homeostasis/metabolism




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory