Phenotypes associated with this allele

• Allele Symbol: Adm^tm1Mtnz
• Allele Name: targeted mutation 1, Alfredo Martinez
• Allele ID: MGI:3811632
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Adm^tm1Mtnz/Adm^tm1Mtnz Tg(Tuba1-cre)1Tes/?	involves: 129S1/Sv * 129S4/SvJaeSor * C3H/HeJ * C57BL/6 * SJL	MGI:3811633

Genotype
MGI:3811633

cn1

• Allelic Composition: Adm^tm1Mtnz/Adm^tm1Mtnz; Tg(Tuba1-cre)1Tes/?
• Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * C3H/HeJ * C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

increased susceptibility to induced morbidity/mortality ( J:138817 )

• increased mortality in hypobaric condition

behavior/neurological

increased anxiety-related response ( J:138817 )

• at 6 and 12 month of age

impaired coordination ( J:138817 )

• at 3 months of age

increased vertical activity ( J:138817 )

• higher levels of horizontal and vertical activity at 3 months of age

• locomotor activity went down as the mice aged, becoming normal level by 9 months of age

increased locomotor activity ( J:138817 )

• higher levels of horizontal and vertical activity at 3 months of age

• locomotor activity went down as the mice aged, becoming normal level by 9 months of age

increased stereotypic behavior ( J:138817 )

• increase on stereotypy for the first 6 months of life