reproductive system
limbs/digits/tail
pigmentation
• melanin production appears reduced
|
integument
sparse hair
(
J:140021
)
• almost no external hairs
|
• expression analysis indicates severely impaired hair shaft differentiation
|
• melanin production appears reduced
|
• fail to form a distinct cortex
|
• fail to form a distinct medulla
|
• wavy appearance
• deeper portions are often misaligned
• proliferating cells are found throughout the hair bulb including the precortex and hair shaft with fewer proliferating cells located at the base of the follicle
• however, normal numbers of follicles are present
|
• often appear less compact
|
• lack vibrissae
• but vibrissae pads form in the normal pattern
|