Phenotypes associated with this allele

• Allele Symbol: Fgf16^tm1Nit
• Allele Name: targeted mutation 1, Nobuyuki Itoh
• Allele ID: MGI:3811646
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ot1	Fgf16^tm1Nit/Y	C57BL/6-Fgf16^tm1Nit	MGI:3811650

Genotype
MGI:3811650

ot1

• Allelic Composition: Fgf16^tm1Nit/Y
• Genetic Background: C57BL/6-Fgf16^tm1Nit

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

decreased heart weight ( J:139637 )

♂ • the heart-weight to body-weight ratio is slightly but significantly reduced in these mice at 6 months of age

heart hypoplasia ( J:139637 )

♂ • the number of cardiomyocytes found in 6 month old hearts is slightly but signicantly reduced

abnormal heart left ventricle morphology ( J:139637 )

♂ • diastolic left ventricle internal dimension is slightly but significantly reduced (3.27 mm vs. 3.63 mm)

abnormal fetal cardiomyocyte proliferation ( J:139637 )

♂ • fetal cardiomyocyte proliferation in both the septum and ventricle is reduced by more than a third at E14.5

muscle

abnormal fetal cardiomyocyte proliferation ( J:139637 )

♂ • fetal cardiomyocyte proliferation in both the septum and ventricle is reduced by more than a third at E14.5

cellular

abnormal fetal cardiomyocyte proliferation ( J:139637 )

♂ • fetal cardiomyocyte proliferation in both the septum and ventricle is reduced by more than a third at E14.5