Phenotypes associated with this allele

• Allele Symbol: Creb3l3^tm1.1Sad
• Allele Name: targeted mutation 1.1, Stephen A Duncan
• Allele ID: MGI:3811836
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Creb3l3^tm1.1Sad/Creb3l3^tm1.1Sad	involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N	MGI:3811850

Genotype
MGI:3811850

hm1

• Allelic Composition: Creb3l3^tm1.1Sad/Creb3l3^tm1.1Sad
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased circulating serum amyloid protein level ( J:140018 )

• mice fail to increase SAP levels in circulation 24 hours after injection with tunicamycin

decreased acute inflammation ( J:140018 )

• mice fail to increase serum amyloid P-component levels after injection with tunicamycin

• mRNAs of other acute phase proteins like C-reactive protein and serum amyloid A3 also fail to increase in the liver 24 hours after tunicamycin injection

homeostasis/metabolism

decreased circulating serum amyloid protein level ( J:140018 )

• mice fail to increase SAP levels in circulation 24 hours after injection with tunicamycin