Phenotypes associated with this allele

• Allele Symbol: Tmprss6^m2Btlr
• Allele Name: mutation 2, Bruce Beutler
• Allele ID: MGI:3812005
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Tmprss6^m2Btlr/Tmprss6^m2Btlr	C57BL/6J-Tmprss6^m2Btlr	MGI:3812006

Genotype
MGI:3812006

hm1

• Allelic Composition: Tmprss6^m2Btlr/Tmprss6^m2Btlr
• Genetic Background: C57BL/6J-Tmprss6^m2Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased circulating iron level ( J:140084 )

• homozygous mutant mice maintained on a standard laboratory diet have a serum iron deficiency

integument

alopecia ( J:140084 )

• the homozygous founder of this lineage developed a normal first coat, but gradually lost hair from its trunk until by ~ 6 weeks of age it was almost nude

• facial hair is retained

progressive hair loss ( J:140084 )

• the homozygous founder of this lineage developed a normal first coat, but gradually lost hair from its trunk until by ~ 6 weeks of age it was almost nude

• facial hair is retained