hematopoietic system
• at 11 weeks of age, the founder mouse had an HbA1c of 11.5%
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homeostasis/metabolism
• at 11 weeks of age, the founder mouse had an HbA1c of 11.5%
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• at 11 weeks of age, the founder mouse had a serum glucose level of 428 mg/dL
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• heterozygous progeny of the founder mouse are hyperinsulinemic
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• heterozygous progeny of the founder mouse have glucosuria
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renal/urinary system
• heterozygous progeny of the founder mouse have glucosuria
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