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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Oxgr1tm1(KOMP)Vlcg
targeted mutation 1, Velocigene
MGI:3812671
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Oxgr1tm1(KOMP)Vlcg/Oxgr1tm1(KOMP)Vlcg involves: BALB/c * C57BL/6NTac MGI:5532484
hm2
Oxgr1tm1(KOMP)Vlcg/Oxgr1tm1(KOMP)Vlcg involves: C57BL/6J * C57BL/6NTac MGI:5550356
cx3
Cysltr1tm1Ykn/Cysltr1tm1Ykn
Cysltr2tm1Ykn/Cysltr2tm1Ykn
Oxgr1tm1(KOMP)Vlcg/Oxgr1tm1(KOMP)Vlcg
involves: BALB/c * C57BL/6 * C57BL/6NTac MGI:5532486


Genotype
MGI:5532484
hm1
Allelic
Composition
Oxgr1tm1(KOMP)Vlcg/Oxgr1tm1(KOMP)Vlcg
Genetic
Background
involves: BALB/c * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oxgr1tm1(KOMP)Vlcg mutation (1 available); any Oxgr1 mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• at low and intermediate doses, mice exhibit reduced leukotriene E4 ligand (LTE4)-induced ear edema compared with wild-type mice
• however, mice exhibit normal leukotriene E4 ligand (LTE4)-, leukotriene C4 (LTC4)- or leukotriene D4 (LTD4)-induced ear edema at higher doses




Genotype
MGI:5550356
hm2
Allelic
Composition
Oxgr1tm1(KOMP)Vlcg/Oxgr1tm1(KOMP)Vlcg
Genetic
Background
involves: C57BL/6J * C57BL/6NTac
Cell Lines 10698C-D12
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oxgr1tm1(KOMP)Vlcg mutation (1 available); any Oxgr1 mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• in mice fed a NaHCO3-rich diet
• in mice fed a NaHCO3-rich diet
• small when fed a standard diet

renal/urinary system
• small when fed a standard diet




Genotype
MGI:5532486
cx3
Allelic
Composition
Cysltr1tm1Ykn/Cysltr1tm1Ykn
Cysltr2tm1Ykn/Cysltr2tm1Ykn
Oxgr1tm1(KOMP)Vlcg/Oxgr1tm1(KOMP)Vlcg
Genetic
Background
involves: BALB/c * C57BL/6 * C57BL/6NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cysltr1tm1Ykn mutation (2 available); any Cysltr1 mutation (11 available)
Cysltr2tm1Ykn mutation (2 available); any Cysltr2 mutation (33 available)
Oxgr1tm1(KOMP)Vlcg mutation (1 available); any Oxgr1 mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• at high doses, mice exhibit reduced leukotriene E4 ligand (LTE4) or leukotriene C4 ligand (LTC4)-induced ear edema compared with wild-type mice
• at low and intermediate doses, mice fail to exhibit leukotriene E4 ligand (LTE4)-, leukotriene C4 ligand (LTC4)- or leukotriene D4 (LTD4)-induced ear edema unlike wild-type mice





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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory