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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ildr2Dbsm1-DBA/2J
DBA/2J
MGI:3814224
Summary 2 genotypes


Genotype
MGI:3814226
hm1
Allelic
Composition		 Ildr2Dbsm1-DBA/2J/Ildr2Dbsm1-DBA/2J
Genetic
Background		 B6.D2-Ildr2Dbsm1-DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ildr2Dbsm1-DBA/2J mutation (0 available); any Ildr2 mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
hyperglycemia ( J:138216 )
• increased blood glucose in males fed a high fat diet for 13 weeks




Genotype
MGI:3814225
cx2
Allelic
Composition		 Ildr2Dbsm1-DBA/2J/Ildr2Dbsm1-DBA/2J
Lepob/Lepob
Genetic
Background		 B6.Cg-Ildr2Dbsm1-DBA/2J Lepob
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ildr2Dbsm1-DBA/2J mutation (0 available); any Ildr2 mutation (27 available)
Lepob mutation (5 available); any Lep mutation (21 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
hyperglycemia ( J:138216 )
• increased fasting blood glucose levels in males up to 120 days of age
decreased circulating insulin level ( J:138216 )
• decreased blood insulin level in males
impaired glucose tolerance ( J:138216 )
• impaired glucose tolerance in males

endocrine/exocrine glands
decreased pancreatic beta cell mass ( J:138216 )
• decreased beta cell mass in males




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory