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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Stxbp5tm1Ytk
targeted mutation 1, Yoshimi Takai
MGI:3814545
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Stxbp5tm1Ytk/Stxbp5tm1Ytk involves: 129X1/SvJ MGI:3814546
hm2
Stxbp5tm1Ytk/Stxbp5tm1Ytk involves: 129X1/SvJ * C57BL * C57BL/6 * DBA MGI:3814548
hm3
Stxbp5tm1Ytk/Stxbp5tm1Ytk involves: 129X1/SvJ * C57BL/6 MGI:3814547


Genotype
MGI:3814546
hm1
Allelic
Composition
Stxbp5tm1Ytk/Stxbp5tm1Ytk
Genetic
Background
involves: 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stxbp5tm1Ytk mutation (0 available); any Stxbp5 mutation (66 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• though fewer than expected mice are born the remainder appear healthy
• fewer than expected mice are born




Genotype
MGI:3814548
hm2
Allelic
Composition
Stxbp5tm1Ytk/Stxbp5tm1Ytk
Genetic
Background
involves: 129X1/SvJ * C57BL * C57BL/6 * DBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stxbp5tm1Ytk mutation (0 available); any Stxbp5 mutation (66 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• the magnitude of long term potentiation is decreased during the first 20 minutes only




Genotype
MGI:3814547
hm3
Allelic
Composition
Stxbp5tm1Ytk/Stxbp5tm1Ytk
Genetic
Background
involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stxbp5tm1Ytk mutation (0 available); any Stxbp5 mutation (66 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• Background Sensitivity: no mice are born after three generation of backcrossing to C57BL/6





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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory