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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Masp2tm1Tefu
targeted mutation 1, Teizo Fujita
MGI:3814550
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Masp2tm1Tefu/Masp2tm1Tefu involves: 129 * C57BL/6 MGI:3814553


Genotype
MGI:3814553
hm1
Allelic
Composition		 Masp2tm1Tefu/Masp2tm1Tefu
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Masp2tm1Tefu mutation (0 available); any Masp2 mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal complement pathway ( J:140667 )
• the lectin-mediated complement pathway is defective in these mice
• there is a 20% reduction in the ability of serum components to cleave C3 and C4 when in the presence of mannose




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory