skeleton
• the interfrontal bone is noticeably larger than controls starting at E16.5
• newborns have an overgrowth of the interfrontal bone in the anterior frontal calvaria
• the frontal bones of five day old mice are structured more trabecularly and have an increased portion of calcified bone matrix
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• three-fold more osteprogenitors are actively proliferating within the frontal sutures of E19.5 fetuses compared to controls
• 1.4 fold more primary osteoblasts of calvaria tissue actively proliferate in vitro compared to controls
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• all osteprogenitors from interfrontal bones differentiate into osteoblasts after three days in culture compared to only half of controls
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• coronal suture closing begins 15 days after birth and is completed by 20 days of age
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• premature fusion of the posterior frontal suture is seen at 5 days after birth
• by 10 days after birth, fusion of the anterior frontal suture becomes evident
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craniofacial
• the interfrontal bone is noticeably larger than controls starting at E16.5
• newborns have an overgrowth of the interfrontal bone in the anterior frontal calvaria
• the frontal bones of five day old mice are structured more trabecularly and have an increased portion of calcified bone matrix
|
short snout
(
J:145520
)
• a shortened craniofacial area is noticeable at one week after birth and worsens as the mice age
|
growth/size/body
short snout
(
J:145520
)
• a shortened craniofacial area is noticeable at one week after birth and worsens as the mice age
|