All Phenotypes Six3<tm3Gco> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Six3^tm3Gco
targeted mutation 3, Guillermo Oliver
MGI:3814869

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Six3^tm3Gco/Six3^tm3Gco Foxg1^tm1(cre)Skm/Foxg1⁺	involves: 129S1/Sv * C57BL/6	MGI:3814903

Allelic Composition	Six3^tm3Gco/Six3^tm3Gco Foxg1^tm1(cre)Skm/Foxg1⁺
Genetic Background	involves: 129S1/Sv * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxg1^tm1(cre)Skm mutation (2 available); any Foxg1 mutation (29 available)
Six3^tm3Gco mutation (0 available); any Six3 mutation (13 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

holoprosencephaly ( J:140315 )

• many display a phenotype typical of holoprosencephaly

• anterior diencephalon is normal

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
holoprosencephaly 2		DOID:0110872	OMIM:157170	J:140315

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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