nervous system
• absent in AgRP neurons
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growth/size/body
• in both males and females on a normal chow diet
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• decrease in weight gain when place on a high fat diet
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adipose tissue
• decrease in weight gain on a high fat diet is solely the result of reduced fat accumulation
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behavior/neurological
• attenuated response to gherlin induced increase in food intake
• however, no difference in baseline food intake is detected
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• increased locomotor activity
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homeostasis/metabolism
• decrease in weight gain when place on a high fat diet
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• on a normal chow diet
• during the transition from a normal chow diet to a high fat diet there is a larger increase in oxygen consumption compared to controls
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• reduced
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