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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Cidectm1Maka
targeted mutation 1, Masato Kasuga
MGI:3815158
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Cidectm1Maka/Cidectm1Maka B6.129P2-Cidectm1Maka MGI:3815175


Genotype
MGI:3815175
hm1
Allelic
Composition
Cidectm1Maka/Cidectm1Maka
Genetic
Background
B6.129P2-Cidectm1Maka
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cidectm1Maka mutation (0 available); any Cidec mutation (15 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• compared to wild-type mice when fed a standard or high fat diet
• compared to wild-type mice when fed a high fat diet
• compared to wild-type mice when fed a standard or high fat diet
• when fed a high fat diet mice weigh less than wild-type mice
• compared to wild-type mice when fed a standard or high fat diet
• when fed a high fat diet, mice exhibit an increased respiratory quotient compared to wild-type mice
• when fed a standard or high fat diet, mice exhibit improved glucose tolerance compared to similarly treated wild-type mice
• basal rates of lipolysis are increased compared to in wild-type adipocytes

adipose tissue
• brown adipocyte fat droplets are larger than in wild-type mice
• epididymal adipose tissue is brown in color unlike in wild-type mice
• subcutaneous and epididymal white adipocytes exhibit multilocular fat droplets that are smaller than in wild-type mice
• white adipocytes have twice as many mitochondria per cell as in wild-type mice
• epididymal and subcutaneous white adipose tissue are less than in wild-type mice
• when fed a high fat diet, mice did not exhibit as much of an increase in adipose tissue as wild-type mice

growth/size/body
• at 16 weeks, mice weigh less than wild-type mice
• when fed a high fat diet mice weigh less than wild-type mice

liver/biliary system
• compared to wild-type mice when fed a high fat diet

integument





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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory