Allele Symbol Allele Name Allele ID |
Scnm1tm1.1Mm targeted mutation 1.1, Miriam Meisler MGI:3818043 |
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Summary |
5 genotypes
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
N |
• mice are viable
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• mice exhibit no abnormal phenotype
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N |
• once the cre transgene is bred out, mice exhibit normal body weights
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N |
• mice exhibit normal grip strength and beam walking ability
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N |
• mice are fertile
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
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♀ | phenotype observed in females |
♂ | phenotype observed in males |
N | normal phenotype |
• in all mice
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• mice exhibit reduced splicing of the Scn8amed-J transcript compared to in wild-type mice and Scn8amed-J Scnm1s double homozygotes
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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