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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mapk8ip3tm1Ysok
targeted mutation 1, Katsuji Yoshioka
MGI:3818507
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Mapk8ip3tm1Ysok/Mapk8ip3tm1Ysok involves: 129P2/OlaHsd * C57BL/6J MGI:3818510
cn2
 		Mapk8ip3tm1Ysok/Mapk8ip3tm1Ysok
Tg(Nes-cre)1Kln/0 		involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL MGI:3818511


Genotype
MGI:3818510
hm1
Allelic
Composition		 Mapk8ip3tm1Ysok/Mapk8ip3tm1Ysok
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mapk8ip3tm1Ysok mutation (0 available); any Mapk8ip3 mutation (53 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:141459 )
• mice appear normal




Genotype
MGI:3818511
cn2
Allelic
Composition		 Mapk8ip3tm1Ysok/Mapk8ip3tm1Ysok
Tg(Nes-cre)1Kln/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mapk8ip3tm1Ysok mutation (0 available); any Mapk8ip3 mutation (53 available)
Tg(Nes-cre)1Kln mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, complete penetrance ( J:141459 )
• no mice are alive at P2
neonatal lethality, incomplete penetrance ( J:141459 )
• despite being born in Mendelian ratios, fewer than expected mice are found at P0 and P1

nervous system
abnormal dorsal telencephalic commissure morphology ( J:141459 )
• mice lack the telencephalic commissure




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory