Phenotypes associated with this allele

• Allele Symbol: Sf1^{Gt(pU17)1Teya}
• Allele Name: gene trap 1, Tesshi Yamada
• Allele ID: MGI:3818622
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Sf1^Gt(pU17)1Teya/Sf1^Gt(pU17)1Teya	involves: C57BL/6 * CBA	MGI:3818624
ht2	Sf1^Gt(pU17)1Teya/Sf1^+	involves: C57BL/6 * CBA	MGI:3818625

Genotype
MGI:3818624

hm1

• Allelic Composition: Sf1^{Gt(pU17)1Teya}/Sf1^{Gt(pU17)1Teya}
• Genetic Background: involves: C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between somite formation and embryo turning, complete penetrance ( J:141491 )

• no mice are present at E8.5

Genotype
MGI:3818625

ht2

• Allelic Composition: Sf1^{Gt(pU17)1Teya}/Sf1⁺
• Genetic Background: involves: C57BL/6 * CBA

neoplasm

increased incidence of tumors by chemical induction ( J:141491 )

• following treatment with azoxymethane, mice exhibit an increased in tumor multiplicity and volume compared to in similarly treated wild-type mice

abnormal tumor morphology ( J:141491 )

• azoxymethane-induced tumors exhibit more atypia with irregular glandular structures and inverted papillary protrusions compared to induced tumors in wild-type mice

homeostasis/metabolism

increased incidence of tumors by chemical induction ( J:141491 )

• following treatment with azoxymethane, mice exhibit an increased in tumor multiplicity and volume compared to in similarly treated wild-type mice