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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Hexim1Gt(XB322)Byg
gene trap XB322, BayGenomics
MGI:3819173
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Hexim1Gt(XB322)Byg/Hexim1Gt(XB322)Byg involves: 129P2/OlaHsd * C57BL/6 MGI:3819181


Genotype
MGI:3819181
hm1
Allelic
Composition
Hexim1Gt(XB322)Byg/Hexim1Gt(XB322)Byg
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hexim1Gt(XB322)Byg mutation (0 available); any Hexim1 mutation (10 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• fewer than expected mice are present after E16.5

cardiovascular system
• at E15.5, coronary arteries exhibit disorganized branching patterns and myocardium vascularization is reduced compared to in wild-type mice
• at E17.5, the myocardial compact layer is reduced in thickness or locally lost unlike in wild-type mice
• at E15.5 but not E13.5, proliferation of cells within the intraventricular septum is increased compared to in wild-type mice
• at E17.5, the ventricular wall is thinner than normal due to increased apoptosis compared to in wild-type mice

muscle
• at E17.5, the myocardial compact layer is reduced in thickness or locally lost unlike in wild-type mice





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory