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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
G6pc2tm1Lex
targeted mutation 1, Lexicon Genetics
MGI:3819785
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
G6pc2tm1Lex/G6pc2tm1Lex involves: 129S5/SvEvBrd * C57BL/6 MGI:3819786


Genotype
MGI:3819786
hm1
Allelic
Composition
G6pc2tm1Lex/G6pc2tm1Lex
Genetic
Background
involves: 129S5/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
G6pc2tm1Lex mutation (0 available); any G6pc2 mutation (24 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• fertility is normal in both males and females

endocrine/exocrine glands
N
• size and number of islets in the pancreas is normal

behavior/neurological

homeostasis/metabolism
• after 6 hours of fasting there is a statistically significant drop in blood glucose
• after 6 hours of fasting female mice show a statistically significant 12% drop in plasma triacylglycerol





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory