Analysis Tools
reproductive system
| N |
• despite reduced fertility and decreased sperm count, testes appear morphologically and histologically similar to controls
• unlike males, females have normal fertility
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• males have about 60% as many spermatozoa as wild-type mice
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• reduced motility in a swim up test
• however, no significant difference in velocity is detected by SMAS analysis, in which spermatozoa are placed in a horizontal chamber
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• homozygous males mated to homozygous or heterozygous females show reduced fertility with only about 24% of matings resulting in pregnancy
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cellular
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• males have about 60% as many spermatozoa as wild-type mice
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• reduced motility in a swim up test
• however, no significant difference in velocity is detected by SMAS analysis, in which spermatozoa are placed in a horizontal chamber
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