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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Nrxn2tm3Sud
targeted mutation 3, Thomas C Sudhof
MGI:3820412
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Nrxn2tm3Sud/Nrxn2tm3Sud involves: 129 * C57BL/6 MGI:3820420


Genotype
MGI:3820420
hm1
Allelic
Composition		 Nrxn2tm3Sud/Nrxn2tm3Sud
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nrxn2tm3Sud mutation (0 available); any Nrxn2 mutation (91 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

growth/size/body
decreased body weight ( J:142107 )
• surviving mice display a 30-40% decrease in body weight compared to controls

nervous system
abnormal inhibitory postsynaptic currents ( J:142107 )
• in cortical slices IPSCs are decreased




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory