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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Gfi1btm1Tmo
targeted mutation 1, Tarik Moroy
MGI:3821577
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Gfi1btm1Tmo/Gfi1btm1Tmo B6.129-Gfi1btm1Tmo MGI:3821578


Genotype
MGI:3821578
hm1
Allelic
Composition
Gfi1btm1Tmo/Gfi1btm1Tmo
Genetic
Background
B6.129-Gfi1btm1Tmo
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gfi1btm1Tmo mutation (1 available); any Gfi1b mutation (21 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• homozygotes are embryonic lethal with development stopping at E15

cardiovascular system
• E15 embryos are pale and have internal hemorrhages

hematopoietic system
• only a small fraction of the cells fully differentiate into erythrocytes in the fetal liver of E15 embryos with an accumulation occurring of Ter119int/CD71int immature cells





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory