All Phenotypes Baz1b<MommeD10> MGI Mouse

Phenotypes associated with this allele

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Baz1b^MommeD10/Baz1b^MommeD10	involves: FVB/N	MGI:3821613
ht2	Baz1b^MommeD10/Baz1b⁺	involves: FVB/N	MGI:3821614

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality ( J:142335 )

• most homozygotes die after birth, in the first week of life

• rare survivors at weaning

growth/size/body

malocclusion ( J:142335 )

short nasal bone ( J:142335 )

• shortened 12% relative to controls

• flattened

prominent forehead ( J:142335 )

• widened bulbous forehead

short snout ( J:142335 )

upturned snout ( J:142335 )

• upward curvature of the nasal tip

decreased body size ( J:142335 )

• at weaning

decreased fetal size ( J:142335 )

• noticable in utero at E18.5

craniofacial

small parietal bone ( J:142335 )

• shortened 12% relative to controls

malocclusion ( J:142335 )

mandible hypoplasia ( J:142335 )

• mandibular hypoplasia, particularly posteriorly

short mandible ( J:142335 )

short nasal bone ( J:142335 )

• shortened 12% relative to controls

• flattened

abnormal palatine bone morphology ( J:142335 )

• reduced in width

prominent forehead ( J:142335 )

• widened bulbous forehead

short snout ( J:142335 )

upturned snout ( J:142335 )

• upward curvature of the nasal tip

skeleton

small parietal bone ( J:142335 )

• shortened 12% relative to controls

malocclusion ( J:142335 )

mandible hypoplasia ( J:142335 )

• mandibular hypoplasia, particularly posteriorly

short mandible ( J:142335 )

short nasal bone ( J:142335 )

• shortened 12% relative to controls

• flattened

abnormal palatine bone morphology ( J:142335 )

• reduced in width

respiratory system

short nasal bone ( J:142335 )

• shortened 12% relative to controls

• flattened

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Williams-Beuren syndrome		DOID:1928	OMIM:194050	J:142335

Allelic Composition	Baz1b^MommeD10/Baz1b⁺
Genetic Background	involves: FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Baz1b^MommeD10 mutation (1 available); any Baz1b mutation (79 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

decreased litter size ( J:142335 )

craniofacial

small parietal bone ( J:142335 )

• shortened 12% relative to controls

short nasal bone ( J:142335 )

• shortened 12% relative to controls

• flattened

abnormal palatine bone morphology ( J:142335 )

• reduced in width

skeleton

small parietal bone ( J:142335 )

• shortened 12% relative to controls

short nasal bone ( J:142335 )

• shortened 12% relative to controls

• flattened

abnormal palatine bone morphology ( J:142335 )

• reduced in width

growth/size/body

short nasal bone ( J:142335 )

• shortened 12% relative to controls

• flattened

respiratory system

short nasal bone ( J:142335 )

• shortened 12% relative to controls

• flattened

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Williams-Beuren syndrome		DOID:1928	OMIM:194050	J:142335

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24