reproductive system
N |
• ovarian function and fertilization are normal
• males are fertile
|
• fail to show any signs of decidualization following artificial induction of the decidual reaction
• endometrial stromal proliferation is severely impaired on days 4 and 5 of pregnancy as the result of a pre-mitotic block leading to impaired cell cycle progression
|
• females are infertile due to a defect in implantation
|
embryo
• fail to show any signs of decidualization following artificial induction of the decidual reaction
• endometrial stromal proliferation is severely impaired on days 4 and 5 of pregnancy as the result of a pre-mitotic block leading to impaired cell cycle progression
|