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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Dlgap5tm1Tfts
targeted mutation 1, Ting-Fen Tsai
MGI:3821727
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Dlgap5tm1Tfts/Dlgap5tm1Tfts involves: 129S7/SvEvBrd MGI:3821728


Genotype
MGI:3821728
hm1
Allelic
Composition
Dlgap5tm1Tfts/Dlgap5tm1Tfts
Genetic
Background
involves: 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dlgap5tm1Tfts mutation (2 available); any Dlgap5 mutation (39 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• ovarian function and fertilization are normal
• males are fertile
• fail to show any signs of decidualization following artificial induction of the decidual reaction
• endometrial stromal proliferation is severely impaired on days 4 and 5 of pregnancy as the result of a pre-mitotic block leading to impaired cell cycle progression
• females are infertile due to a defect in implantation

embryo
• fail to show any signs of decidualization following artificial induction of the decidual reaction
• endometrial stromal proliferation is severely impaired on days 4 and 5 of pregnancy as the result of a pre-mitotic block leading to impaired cell cycle progression





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory