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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ncor1tm1Anh
targeted mutation 1, Anthony N Hollenberg
MGI:3821874
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Ncor1tm1Anh/Ncor1tm1Anh
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ 		involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * DBA MGI:3821875


Genotype
MGI:3821875
cn1
Allelic
Composition		 Ncor1tm1Anh/Ncor1tm1Anh
Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic
Background		 involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * DBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ncor1tm1Anh mutation (1 available); any Ncor1 mutation (396 available)
Speer6-ps1Tg(Alb-cre)21Mgn mutation (6 available); any Speer6-ps1 mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased circulating thyroxine level ( J:142045 )
• male mice exhibit a slight decrease in plasma T4 levels compared to in Ncor1tm1Anh control mice
decreased circulating LDL cholesterol level ( J:142045 )
• PTU treated mice exhibit decreased serum LDL cholesterol levels compared to in similarly treated Ncor1tm1Anh control mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory