All Phenotypes Ncor1<tm1Anh> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ncor1^tm1Anh
targeted mutation 1, Anthony N Hollenberg
MGI:3821874

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Ncor1^tm1Anh/Ncor1^tm1Anh Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺	involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * DBA	MGI:3821875

Allelic Composition	Ncor1^tm1Anh/Ncor1^tm1Anh Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺
Genetic Background	involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6 * DBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ncor1^tm1Anh mutation (1 available); any Ncor1 mutation (396 available)
Speer6-ps1^{Tg(Alb-cre)21Mgn} mutation (6 available); any Speer6-ps1 mutation (4 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

homeostasis/metabolism

decreased circulating thyroxine level ( J:142045 )

• male mice exhibit a slight decrease in plasma T4 levels compared to in Ncor1^tm1Anh control mice

decreased circulating LDL cholesterol level ( J:142045 )

• PTU treated mice exhibit decreased serum LDL cholesterol levels compared to in similarly treated Ncor1^tm1Anh control mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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