Phenotypes associated with this allele

• Allele Symbol: Snap25^tm1Bark
• Allele Name: targeted mutation 1, Christina Bark
• Allele ID: MGI:3821973
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Snap25^tm1Bark/Snap25^tm1Bark	B6.Cg-Snap25^tm1Bark	MGI:3821975

Genotype
MGI:3821975

hm1

• Allelic Composition: Snap25^tm1Bark/Snap25^tm1Bark
• Genetic Background: B6.Cg-Snap25^tm1Bark

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

tremors ( J:142096 )

hyperactivity ( J:142096 )

• at P10, mice exhibit extreme activity with hyperactive episodes unlike wild-type mice

seizures ( J:142096 )

nervous system

seizures ( J:142096 )

decreased paired-pulse facilitation ( J:142096 )

• at 0.2 Hz and 0.5 Hz

hearing/vestibular/ear

impaired hearing ( J:142096 )

• mice are delayed compared to wild-type mice in their ability to respond to sound

skeleton

decreased width of hypertrophic chondrocyte zone ( J:142096 )

• in the tibia and femur

vision/eye

delayed eyelid opening ( J:142096 )

• eye opening was delayed by 1 day compared to in wild-type mice

growth/size/body

decreased body size ( J:142096 )

• at P10

decreased body weight ( J:142096 )

• during the first week after birth