Analysis Tools|
Allele Symbol Allele Name Allele ID |
Gt(ROSA)26Sortm1(Hesx1)Jpmb targeted mutation 1, Juan Pedro Martinez Barbera MGI:3822482 |
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| Summary |
4 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• 10% of embryos exhibit exencephaly
• Background Sensitivity: phenotype is background-dependent, as mutants on C57BL/6J;CD-1 background do not display exencephaly
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• 80% of embryos exhibit exencephaly
• Background Sensitivity: phenotype is background-dependent, as mutants on C57BL/6J;CD-1 background do not display exencephaly
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice surviving to weaning age are reduced in number when compared to expected numbers
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• all mutants surviving to weaninig age display eye defects
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
| N |
• number of mice identified at weaning is similar to the expected numbers
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• all mutants surviving to weaninig age display eye defects
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• bilateral microphthalmia was seen in some embryos
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• some embryos show bilateral anophthalmia, whereas others have unilateral anophthalmia
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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