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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Septin3tm1Wtr
targeted mutation 1, William S Trimble
MGI:3822551
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Septin3tm1Wtr/Septin3tm1Wtr involves: 129S1/Sv * 129X1/SvJ * CD-1 MGI:3822553
cx2
 		Septin3tm1Wtr/Septin3tm1Wtr
Septin5tm1Wtr/Septin5tm1Wtr 		involves: 129S1/Sv * 129X1/SvJ * CD-1 MGI:3822554


Genotype
MGI:3822553
hm1
Allelic
Composition		 Septin3tm1Wtr/Septin3tm1Wtr
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Septin3tm1Wtr mutation (0 available); any Septin3 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:142823 )
N
• mice exhibit normal axon outgrowth, hippocampal architecture, nerve terminal ultrastructure, paired pulse facilitation, excitatory postsynaptic current, synaptic vesicle pool recycling, replenishment of immediately releasable pool of synaptic vesicles, and replenishment of readily releasable pool of synaptic vesicles




Genotype
MGI:3822554
cx2
Allelic
Composition		 Septin3tm1Wtr/Septin3tm1Wtr
Septin5tm1Wtr/Septin5tm1Wtr
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * CD-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Septin3tm1Wtr mutation (0 available); any Septin3 mutation (25 available)
Septin5tm1Wtr mutation (0 available); any Septin5 mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:142823 )
N
• mice exhibit normal axon outgrowth, hippocampal architecture, nerve terminal ultrastructure, paired pulse facilitation, excitatory postsynaptic current, synaptic vesicle pool recycling, replenishment of immediately releasable pool of synaptic vesicles, and replenishment of readily releasable pool of synaptic vesicles




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory