About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		M14104Asr
mutation 14104, Apurva K Srivastava
MGI:3823051
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		M14104Asr/M14104Asr+ C57BL/6J-M14104Asr MGI:3823052
cx2
 		Ghrhrlit/Ghrhr+
M14104Asr/M14104Asr+ 		C57BL/6J-Ghrhrlit M14104Asr MGI:3823055
cx3
 		Ghrhrlit/Ghrhrlit
M14104Asr/M14104Asr+ 		C57BL/6J-Ghrhrlit M14104Asr MGI:3823056


Genotype
MGI:3823052
ht1
Allelic
Composition		 M14104Asr/M14104Asr+
Genetic
Background		 C57BL/6J-M14104Asr
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body weight ( J:141536 )

skeleton
decreased diameter of femur ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the femur are reduced; however, the cortical thickness and the length is similar to control
decreased diameter of tibia ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the tibia are reduced; however, the cortical thickness and the length is similar to control
increased volumetric bone mineral density ( J:141536 )
• increased volumetric bone density
decreased bone mass ( J:141536 )
• the body weight adjusted bone size was lower

limbs/digits/tail
decreased diameter of femur ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the femur are reduced; however, the cortical thickness and the length is similar to control
decreased diameter of tibia ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the tibia are reduced; however, the cortical thickness and the length is similar to control




Genotype
MGI:3823055
cx2
Allelic
Composition		 Ghrhrlit/Ghrhr+
M14104Asr/M14104Asr+
Genetic
Background		 C57BL/6J-Ghrhrlit M14104Asr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ghrhrlit mutation (3 available); any Ghrhr mutation (34 available)
M14104Asr mutation (0 available); any M14104Asr mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body weight ( J:141536 )

skeleton
decreased diameter of femur ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the femur are reduced; however, the cortical thickness and the length is similar to control
decreased diameter of tibia ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the tibia are reduced; however, the cortical thickness and the length is similar to control
increased volumetric bone mineral density ( J:141536 )
• increased volumetric bone density
decreased bone mass ( J:141536 )
• the body weight adjusted bone size was lower
• the magnitude of bone size phenotype is significantly enhanced by presence of Ghrhrlit allele

limbs/digits/tail
decreased diameter of femur ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the femur are reduced; however, the cortical thickness and the length is similar to control
decreased diameter of tibia ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the tibia are reduced; however, the cortical thickness and the length is similar to control




Genotype
MGI:3823056
cx3
Allelic
Composition		 Ghrhrlit/Ghrhrlit
M14104Asr/M14104Asr+
Genetic
Background		 C57BL/6J-Ghrhrlit M14104Asr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ghrhrlit mutation (3 available); any Ghrhr mutation (34 available)
M14104Asr mutation (0 available); any M14104Asr mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body weight ( J:141536 )

skeleton
decreased diameter of femur ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the femur are reduced; however, the cortical thickness and the length is similar to control
decreased diameter of tibia ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the tibia are reduced; however, the cortical thickness and the length is similar to control
increased volumetric bone mineral density ( J:141536 )
• increased volumetric bone density
decreased bone mass ( J:141536 )
• the body weight adjusted bone size was lower
• the magnitude of bone size phenotype is significantly enhanced by presence of Ghrhrlit allele

limbs/digits/tail
decreased diameter of femur ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the femur are reduced; however, the cortical thickness and the length is similar to control
decreased diameter of tibia ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the tibia are reduced; however, the cortical thickness and the length is similar to control




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory