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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		M14104Asr
mutation 14104, Apurva K Srivastava
MGI:3823051
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		M14104Asr/M14104Asr+ C57BL/6J-M14104Asr MGI:3823052
cx2
 		Ghrhrlit/Ghrhr+
M14104Asr/M14104Asr+ 		C57BL/6J-Ghrhrlit M14104Asr MGI:3823055
cx3
 		Ghrhrlit/Ghrhrlit
M14104Asr/M14104Asr+ 		C57BL/6J-Ghrhrlit M14104Asr MGI:3823056


Genotype
MGI:3823052
ht1
Allelic
Composition		 M14104Asr/M14104Asr+
Genetic
Background		 C57BL/6J-M14104Asr
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body weight ( J:141536 )

skeleton
decreased diameter of femur ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the femur are reduced; however, the cortical thickness and the length is similar to control
decreased diameter of tibia ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the tibia are reduced; however, the cortical thickness and the length is similar to control
increased volumetric bone mineral density ( J:141536 )
• increased volumetric bone density
decreased bone mass ( J:141536 )
• the body weight adjusted bone size was lower

limbs/digits/tail
decreased diameter of femur ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the femur are reduced; however, the cortical thickness and the length is similar to control
decreased diameter of tibia ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the tibia are reduced; however, the cortical thickness and the length is similar to control




Genotype
MGI:3823055
cx2
Allelic
Composition		 Ghrhrlit/Ghrhr+
M14104Asr/M14104Asr+
Genetic
Background		 C57BL/6J-Ghrhrlit M14104Asr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ghrhrlit mutation (3 available); any Ghrhr mutation (34 available)
M14104Asr mutation (0 available); any M14104Asr mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body weight ( J:141536 )

skeleton
decreased diameter of femur ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the femur are reduced; however, the cortical thickness and the length is similar to control
decreased diameter of tibia ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the tibia are reduced; however, the cortical thickness and the length is similar to control
increased volumetric bone mineral density ( J:141536 )
• increased volumetric bone density
decreased bone mass ( J:141536 )
• the body weight adjusted bone size was lower
• the magnitude of bone size phenotype is significantly enhanced by presence of Ghrhrlit allele

limbs/digits/tail
decreased diameter of femur ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the femur are reduced; however, the cortical thickness and the length is similar to control
decreased diameter of tibia ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the tibia are reduced; however, the cortical thickness and the length is similar to control




Genotype
MGI:3823056
cx3
Allelic
Composition		 Ghrhrlit/Ghrhrlit
M14104Asr/M14104Asr+
Genetic
Background		 C57BL/6J-Ghrhrlit M14104Asr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ghrhrlit mutation (3 available); any Ghrhr mutation (34 available)
M14104Asr mutation (0 available); any M14104Asr mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased body weight ( J:141536 )

skeleton
decreased diameter of femur ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the femur are reduced; however, the cortical thickness and the length is similar to control
decreased diameter of tibia ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the tibia are reduced; however, the cortical thickness and the length is similar to control
increased volumetric bone mineral density ( J:141536 )
• increased volumetric bone density
decreased bone mass ( J:141536 )
• the body weight adjusted bone size was lower
• the magnitude of bone size phenotype is significantly enhanced by presence of Ghrhrlit allele

limbs/digits/tail
decreased diameter of femur ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the femur are reduced; however, the cortical thickness and the length is similar to control
decreased diameter of tibia ( J:141536 )
• significantly slender bones
• both periosteal and endosteal circumference and cross-sectional area at the mid shaft of the tibia are reduced; however, the cortical thickness and the length is similar to control




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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory