About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Arg1tm1.1Pmu
targeted mutation 1.1, Peter J Murray
MGI:3826848
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Arg1tm1.1Pmu/Arg1tm1.1Pmu involves: C57BL/6 * NZB MGI:3826859


Genotype
MGI:3826859
hm1
Allelic
Composition		 Arg1tm1.1Pmu/Arg1tm1.1Pmu
Genetic
Background		 involves: C57BL/6 * NZB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arg1tm1.1Pmu mutation (0 available); any Arg1 mutation (28 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality ( J:143229 )
• gross phenotype is stated to be identical to that of Arg1tm1Rki homozygotes; however, no data are provided

immune system
increased macrophage nitric oxide production ( J:143229 )
• macrophages produce more nitrous oxide in response to LPS stimulation or Mycobacterium bovis infection

homeostasis/metabolism
increased macrophage nitric oxide production ( J:143229 )
• macrophages produce more nitrous oxide in response to LPS stimulation or Mycobacterium bovis infection

hematopoietic system
increased macrophage nitric oxide production ( J:143229 )
• macrophages produce more nitrous oxide in response to LPS stimulation or Mycobacterium bovis infection




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory