All Phenotypes Vegfd<tm1Hrl> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Vegfd^tm1Hrl
targeted mutation 1, H R Lijnen
MGI:3826978

Summary

2 genotypes

Allelic Composition	Vegfd^tm1Hrl/Y
Genetic Background	B6.129S-Vegfd^tm1Hrl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vegfd^tm1Hrl mutation (0 available); any Vegfd mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

decreased metastatic potential ( J:153734 )

• transplanted PancO2 adenocarcinomas exhibit a 2-fold reduction in lymphatic metastasis compared to in similarly treated wild-type mice

Allelic Composition	Vegfd^tm1Hrl/Y
Genetic Background	involves: 129S/SvEv * Swiss

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vegfd^tm1Hrl mutation (0 available); any Vegfd mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

increased food intake ( J:143070 )

• when fed a standard diet, mice exhibit increased food intake compared to wild-type mice

• however, mice fed a high fat diet exhibit normal food intake

adipose tissue

adipose tissue phenotype ( J:143070 )

N	• mice exhibit normal adipose tissue morphology when fed a standard or high fat diet

growth/size/body

growth/size/body region phenotype ( J:143070 )

N	• mice exhibit normal body weights when fed a standard or high fat diet

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:153734 )

N	• mice exhibit normal wound healing

immune system

immune system phenotype ( J:153734 )

N	• mice exhibit normal lymphangiogenesis

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24