All Phenotypes Vegfd<tm1Hrl> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Vegfd^tm1Hrl
targeted mutation 1, H R Lijnen
MGI:3826978

Summary

2 genotypes

Allelic Composition	Vegfd^tm1Hrl/Y
Genetic Background	B6.129S-Vegfd^tm1Hrl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vegfd^tm1Hrl mutation (0 available); any Vegfd mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

decreased metastatic potential ( J:153734 )

• transplanted PancO2 adenocarcinomas exhibit a 2-fold reduction in lymphatic metastasis compared to in similarly treated wild-type mice

Allelic Composition	Vegfd^tm1Hrl/Y
Genetic Background	involves: 129S/SvEv * Swiss

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vegfd^tm1Hrl mutation (0 available); any Vegfd mutation (15 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

increased food intake ( J:143070 )

• when fed a standard diet, mice exhibit increased food intake compared to wild-type mice

• however, mice fed a high fat diet exhibit normal food intake

adipose tissue

adipose tissue phenotype ( J:143070 )

N	• mice exhibit normal adipose tissue morphology when fed a standard or high fat diet

growth/size/body

growth/size/body region phenotype ( J:143070 )

N	• mice exhibit normal body weights when fed a standard or high fat diet

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:153734 )

N	• mice exhibit normal wound healing

immune system

immune system phenotype ( J:153734 )

N	• mice exhibit normal lymphangiogenesis

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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